Novel blood group H glycolipid antigens exclusively expressed in blood group A and AB erythrocytes (type 3 chain H). I. Isolation and chemical characterization.

Novel blood group H glycolipid antigens exclusively expressed in blood group A and AB erythrocytes (type 3 chain H). I. Isolation and chemical characterization.

A series of blood group H antigens reacting with monoclonal antibody MBrl has been found in human blood group A and AB erythrocytes, but not in O or B erythrocytes. These H antigens are clearly different from the globo-H structure (Fuc alpha 1----2Gal beta 1----3GalNAc beta 1----3Gal alpha 1----4Gal beta 1----4Glc beta 1----1Cer), which was previously isolated from O erythrocytes and is also re...

A new series of blood group A and H antigens expressed in human erythrocytes and the incompatible A antigens expressed in tumours of blood group O and B individuals.

Tipe 2 chain A and H antigens qf' human erythrocytes Results of previous studies from our laboratories on the isolation and characterization of erythrocyte glycolipids with blood group A and B activities can be summarized as follows: ( I ) Four A-active and four H-active glycosphingolipid components, termed A", Ah, A , Ad, and H I , H,, H, and H,, have been isolated and their structures have be...

Blood Group A Glycolipid Antigen Expression in Kidney, Ureter, Kidney Artery, and Kidney Vein from a Blood Group A,Le(a-b+) Human Individual EVIDENCE FOR A NOVEL BLOOD GROUP A HEPTAGLYCOSYLCERAMIDE BASED ON A TYPE 3 CARBOHYDRATE CHAIN*

Kidney, ureter, kidney artery, and kidney vein tissue were obtained from a single human transplant specimen. The donors erythrocyte blood group phenotype was AILe(a-b+). Total non-acid glycolipid fractions were isolated and individual glycolipid components were identified by immunostaining thin layer plates with a panel of monoclonal antibodies and by mass spectrometry of the permethylated and ...

Characterization of a blood group H type pentaglycosylceramide of human pancreas based on a type 1 carbohydrate chain.

Blood group A-like glycolipid and a novel Forssman antigen in the hepatocarcinoma of a blood group O individual.

Two glycolipid fractions that inhibit Blood Group A hemagglutination were isolated from hepatocarcinoma tissue of a Blood Group O individual. One fraction corresponding to a ceramide pentato hexasaccharide weakly inhibited hemagglutination caused by blood group anti-A sera and gave a precipitin reaction with Rana catesbiana lectin. The fraction had no Forssman activity, showed a single spot on ...